Established in 1915 on the former Patterson Farm in Appleton, just five kilometres east of Carleton Place, Mississippi Golf Club is one of the oldest clubs in Ontario.

Mississippi began as a nine-hole course, with a second nine - designed by the renowned golf course architect Graham Cooke - added in 1987. A new Pro Shop was constructed in 1992 to serve a growing membership. The original stone club house was destroyed by fire in the fall of 1997, and replaced with a modern new building that opened the following spring.